Laboratory Sciences Core (D)

Aims

  1. To support investigator needs and provide specialized immunologic assays for innate and adaptive immunity in the Immunology Sub-Core
  2. To provide gene expression assays and advanced HIV-focused bioinformatics in the Genomics Sub-Core through an Integrated Bioinformatics Network (IBN), in partnership with the Case Western Reserve University CFAR
  3. To provide specialized virology assays for viral reservoir studies and elutriated human monocytes in the Virology Sub-Core
  4. To provide education, mentoring, consultation, training and assistance for laboratory assays to graduate students, pilot grant awardees and Early Stage Investigators
  5. To promote basic science research in clinical trial settings including behavioral interventions and projects related to EHE
  6. Promote inter-CFAR collaborations with basic science cores for resources and technology

Great resource

Capturing Participant Information for Mucosal Sampling: An Investigators Guide
Published by the Global HIV Vaccine Enterprise* with the support of the
National Institute of Allergy and Infectious Diseases and the HIV Mucosal Immunology Group. 1st edition, May 2014
Take a look at The Guide To order copies of the booklet version of The Guide, email timelytopics@vaccineenterprise.org

About the Global HIV Vaccine Enterprise

The Global HIV Vaccine Enterprise (the Enterprise) is a unique collaboration of the
world’s leading HIV vaccine research funding, policymaking, advocacy and
stakeholder organizations dedicated to working together to advance HIV
vaccine research and development. Recognizing that no single institution, country or individual can develop an HIV vaccine in isolation, the Enterprise promotes
and facilitates coordination, collaboration, knowledge sharing and resource optimization. A small Secretariat supports the Enterprise, helping to catalyze the activities of this collaboration and implement programming to move its mission forward.

Microbiome Analysis

Core D can facilitate microbiome sequencing through a Core agreement with the University of Minnesota. Please contact Margie Roach (305-243-4822) for details.





Savita Pahwa, M.D.

Savita Pahwa, M.D.

Research Profile

Savita Pahwa, MD is Professor of Microbiology and Immunology, and Professor in Pediatrics and Medicine at the University of Miami Miller School of Medicine in Miami, USA. She serves as the Director of the Miami Center for AIDS Research and as the Director of the Laboratory Sciences Core of the Miami CFAR.

Dr Pahwa received her medical education at the Lady Harding Medical College in New Delhi, India, and specialized in Immunology at the Memorial Hospital and Sloan Kettering Institute in New York, USA. She served as Chief of Allergy and Immunology and Director of the HIV program in the Department of Pediatrics at North Shore –Long Island Jewish Medical Center in Manhasset, NY for several years before moving to the University of Miami in 2004.

Dr Pahwa’s expertise is in immunology and immune deficiency diseases including HIV/AIDS. Her research interests are in HIV immunopathogenesis, the influence of aging and inflammation, cytokines as vaccine adjuvants, HIV reservoirs, and strategies aimed to cure HIV/AIDS. She is investigating cellular and molecular mechanisms of T-B cell interaction in antibody production in different patient groups using state-of –art tools. She is an investigator in the HIV Clinical Trials Unit at the University of Miami.

Sion Williams, PhD

Research Profile

In addition to his responsibilities in the OCF (Oncogenomics Core Facility) at the Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine, Sion Williams, PhD, is also a Research Assistant Professor in the Department of Neurology. Dr. Williams has a strong background in molecular biology and has focused his research on the molecular genetics of mitochondria. His research focuses on the somatic mutation spectra of mitochondrial DNA (mtDNA) and on nuclease-mediated gene therapy for mtDNA disorders. Dr. Williams also has a strong interest in next generation sequencing and in genomics technology.